Background
Methods
Study design
Study population
Data processing and analysis
Results
Epidemiological data
Number | % | |
---|---|---|
Age (years) | ||
[25–35] | 3 | 9.4 |
[35–45] | 11 | 34.3 |
[45–55] | 10 | 31.25 |
[55–65] | 3 | 9.4 |
[65–75] | 3 | 9.4 |
[75–85] | 2 | 6.25 |
Profession | ||
Housewife | 12 | 37.5 |
Farmer | 7 | 21.9 |
Liberal profession | 7 | 21.9 |
Civil servant | 4 | 12.5 |
Student | 2 | 6.2 |
Risk factors | ||
Yes | 27 | 84.4 |
HPV* infection | 9 | 33.3 |
Multiple sexual partners | 6 | 22.2 |
Family history of vulvar cancer | 5 | 18.5 |
Personal history of cervical cancer | 5 | 18.5 |
Dysplastic lesions | 5 | 18.5 |
Smoking | 3 | 11.1 |
History of cervical cancer | 1 | 3.7 |
Pathological data
Value | % | |
---|---|---|
Ulcer-bourgeoning tumor | 10 | 31.3 |
Ulcerated tumor | 8 | 25 |
Infiltrating tumor | 5 | 15.6 |
Nodular tumor | 5 | 15.6 |
Budding tumor | 4 | 12.5 |
Total | 32 | 100 |
Histological types | |||||
---|---|---|---|---|---|
squamous cell carcinoma | Adenocarcinoma | Melanoma | Total | p-value | |
n (%) | n (%) | n (%) | n (%) | ||
HPV* infection | 5(55.6) | 4(44.4) | 0(0) | 9(100) | 0.041 |
Multiple sexual partners | 4(66.7) | 0(0) | 2(33.3) | 6(100) | 0.1491 |
Family history of vulvar cancer | 3(60) | 0(0) | 2(40) | 5(100) | 0.139 |
Personal history of cervical cancer | 4(80) | 1(20) | 0(0) | 5(100) | 1 |
Dysplastic lesions | 3(60) | 2(40) | 0(0) | 5(100) | 0.322 |
Smoking | 1(33.3) | 0(0) | 2(66.7) | 3(100) | 0.051 |
Family history of cervical cancer | 1(100) | 0(0) | 0(0) | 1(100) | 1 |
Histological types | ||||
---|---|---|---|---|
Well differentiated (25) | Poorly differentiated (3) | Total (28) | p-value | |
n (%) | n (%) | n (%) | ||
HPV* infection | 8(88.9) | 1(11.1) | 9(100) | 0.0068 |
Personal history of cervical cancer | 4(80) | 1(20) | 5(100) | 0.22 |
Dysplastic lesions | 5(100) | 0(0) | 5(100) | 1.07 |
Multiple sexual partners | 4(100) | 0(0) | 4(100) | 0.94 |
Family history of vulvar cancer | 3(100) | 0(0) | 3(100) | 0.601 |
Smoking | 1(100) | 0(0) | 1(100) | 1.788 |
Family history of cervical cancer | 1(100) | 0(0) | 1(100) | 2.011 |
Univariate analysis | Multivariate analysis | |||||||
---|---|---|---|---|---|---|---|---|
Good differentiation | ||||||||
n/N | % | OR | 95% CI | p-value | ORa | 95% CI | p-value | |
Age (years) | 0.23 | |||||||
[25–35] | 3 / 3 | 100 | 1 | |||||
[35–45] | 9 / 10 | 90 | 0.62 | 0.45–2.77 | ||||
[45–55] | 9 / 9 | 100 | ||||||
[55–65] | 2 / 2 | 100 | ||||||
[65–75] | 1 / 3 | 33.3 | 0.71 | 0.34–1.88 | ||||
[75–85] | 1 / 1 | 100 | ||||||
Histological types | 0.0004 | 0.001 | ||||||
Adenocarcinoma | 6 / 6 | 100 | 1 | 1 | ||||
Squamous cell carcinoma | 19 / 22 | 86.4 | 0.74 | 0.25–0.96 | 0.55 | 0.4–0.81 | ||
Risk factors | 0.073 | |||||||
Yes | 22 / 24 | 91.7 | 1.39 | 1.24–1.92 | ||||
No | 3 / 4 | 75 | 1 |